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An unusual scrotal mass: Morphological clues |
Poojan Agarwal( ),Anila Sharma,Sunil Pasricha,Anurag Mehta
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Department of Laboratory Services, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, India |
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Received: 03 September 2018
Available online: 20 January 2021
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Corresponding Authors:
Poojan Agarwal
E-mail: poojanagarwal@gmail.com
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Morphological differentials/IHC | Rhabdomyosarcoma | Undifferentiated sarcoma | Sex cord stromal tumor | Seminoma | CK | - | - | +/- | - | Vimentin | + | + | - | + | s-100 | - | - | - | - | CD34 | - | + | - | - | Myogenin | + | - | - | - | Desmin | + | - | - | - | SALL-4 | - | - | - | + | PLAP | - | - | Not known | + | SF-1 | - | - | + | - | Inhibin | - | - | + | - |
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Morphological differentials and their differentiating IHC profile.
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Gross picture of the testicular tumor.
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Micro-photographs of the testicular tumor. (A) Tumor tissue abutting seminiferous tubules (100×; H&E); (B) Multinucleate tumor cells with abundant eosinophilic cytoplasm and peripherally pushed nuclei suggestive of rhabdoid differentiation (400×; H&E); (C) Scattered tadpole shaped cell seen in the center of field (400×; H&E); (D) Bizarre tumor cells with scattered mitotic figure (400×; H&E); (E) Immunohistochemical stain for desmin (400×); (F) Immunohistochemical stain for myogenin (400×).
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[1] |
Aydin GB, Cift?i AO, Yal?in B, Ak??ren Z, Ca?lar M, Senocak ME, et al. Paratesticular metastasis from Wilms tumor associated with a hydrocele. Pediatr Blood Cancer 2006; 47:97-9.
|
[2] |
Khoubehi B, Mishra V, Motiwala H, Karim O. Adult paratesticulartumors. BJU Int 2002; 90:707-15.
|
[3] |
Kumar R, Kapoor R, Khosla D, Kumar N, Ghoshal S, Mandal AK, et al. Paratesticular rhabdomyosarcoma in young adults: a tertiary care institute experience. Indian J Urol 2013; 29:110-3.
|
[4] |
Huddart RA, Patrikidou A. Paratesticular tumors. In: Pagliaro L, editor. Rare genitourinary tumors. 1st ed. Switzerland: Springer; 2016. p. 261-80.
|
[5] |
Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. WHO classification of tumors of soft tissue and bone. Lyon: WHO Press; 2013. p. 127.
|
[6] |
Hettmer S, Archer NM, Somers GR, Novokmet A, Wagers AJ, Diller L, et al. Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers. Cancer 2014; 120:1068-75.
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