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Sheathless and fluoroscopy-free retrograde intrarenal surgery: An attractive way of renal stone management in high-volume stone centers |
Sarwar Noori Mahmooda,*(),Hewa Toffeqb,Saman Fakhralddinb
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a University of Sulaimani College of Medicine, Kurdistan, Iraq b Sulaimania General Teaching Hospital, Sulaimania, Iraq |
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Abstract Objective: To evaluate the efficacy and safety of sheathless and fluoroscopy-free flexible ureterorenoscopic laser lithotripsy (FURSL) for treating renal stones. Methods: Between May 2015 and May 2017, 135 patients with renal stones treated with sheathless and fluoroscopy-free FURSL were prospectively evaluated. Our technique involved a semi-rigid ureteroscopic assessment of the ureter, and the guidewire was left in situ to railroad the flexible ureteroscope. A holmium laser was used to fragment and dust the stones; fragments were neither grasped nor collected. Results: The study population consisted of 135 patients including 85 males (62.96%) and 50 females (37.04%) with a mean age of 40.65 years (range: 3-70 years) were evaluated. The mean stone size was 17.23 mm (range: 8-41 mm). Complete stone-free status was achieved in 122 (90.37%) patients and clinically insignificant residual fragments (CIRF) in two (1.48%), while residual stones were still present in 11 (8.15%) patients. Postoperative complications occurred in 23 (17.4%) cases and were mostly minor, including fever in 17 (12.6%), pyelonephritis in four (3.0%), subcapsular hematoma in one (0.7%) and steinstrasse in one (0.7%). These complications were Clavien I-II, GI in 17 (12.6%) patients, GII in five (3.7%), and Clavien IIIb in one (0.7%). No major complications were observed. Stone size ≥2 cm, operative time ≥30 min, and lasing time ≥20 min were significantly associated with a higher rate of complications and lower stone-free rates upon univariate analysis (p<0.05). Conclusion: Sheathless and fluoroscopy-free FURSL are effective and safe for renal stone management, especially for stones under 2 cm in diameter. This process is a feasible option for avoiding sheath complications, which can protect surgeons from the negative effects of radiation.
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Received: 27 November 2018
Available online: 20 July 2020
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Corresponding Authors:
Sarwar Noori Mahmood
E-mail: sarwarchalabi@yahoo.com
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Variable | Case | Case no., n | 135 | Age (year), mean±SD (range) | 40.65±12.96 (3-70) | Gender, n (%) | Male | 85 (62.96) | Female | 50 (37.04) | Stone laterality, n (%) | Right side | 65 (48.15) | Left side | 70 (51.85) | Stone size (mm), mean±SD (range) | 17.23±6.69 (8-41) | Stone number, n (%) | Single stone | 92 (68.15) | Multiple stone | 43 (31.85) | Stone location, n (%) | Lower calyx | 29 (21.48) | Pelvis | 76 (56.30) | Upper/middle calyx | 30 (22.22) | Previous stone related intervention, n (%) | PCNL | 8 (5.92) | USR | 14 (10.37) | ESWL | 10 (7.41) | Open renal surgery | 5 (3.70) | Renal anomalies | Pelvic kidney | 2 (1.48) | PUJ obstruction | 3 (2.22) | Malrotated kidney | 2 (1.48) | Horseshoe kidney | 1 (0.74) | Double moiety | 1 (0.74) | Comorbidity, n (%) | Hypertensive | 33 (24.44) | Diabetic | 22 (16.30) | Using anticoagulant drugs | 05 (3.70) | Renal failure | 10 (7.40) | Preoperative double-J stenting, n (%) | 8 (5.93) |
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The demographic data of patients and stone characteristics.
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Stone-free rate according to the stone size.
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Incidence of complication according to the stone size.
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Variable | Value | Mean operative time (SD, range), min | 32.47 (10.09, 13-60) | Mean lasing time (SD, range), min | 22.15 (8.68, 6-45) | Use of fluoroscopy guidance, n (%) | 0 (0.0) | Postoperative double-J stenting, n (%) | 135 (100) | Mean hospital stay (SD, range), h | 19.29 (8.83, 10-48) | SFR, n/N (%) | ≤10 mm | 20/20 (100) | >10-20 mm | 70/76 (92.10) | >20-30 mm | 25/30 (83.33) | ≥30 mm | 7/9 (77.78) | Lower calyx | 25/29 (86.21) | Pelvis | 71/76 (93.42) | Upper/middle calyx | 26/30 (86.67) | Stone clearance, n/N (%) | Complete clearance | 122/135 (90.37) | Clinically non-significant residual stone | 2/135 (1.48) | Residual | 11/135 (8.15) | Duration of stone clearance, n/N (%) | Immediate | 44/135 (32.59) | After 2 weeks | 99/135 (73.33) | After 6 weeks | 122/135 (90.37) | After 3 months | 122/135 (90.37) | The ancillary procedure, n (%) | ESWL | 11 (8.15) | RIRS | 1 (0.74) | Complication, n/N (%) | ≤10 mm | 1/20 (5.00) | >10-20 mm | 10/76 (13.16) | >20-30 mm | 7/30 (23.33) | ≥30 mm | 5/9 (55.56) | Lower calyx | 3/29 (10.34) | Pelvis | 16/76 (21.05) | Upper/middle calyx | 4/30 (13.33) | Clavien Grade I, n/N (%) | Fever | 17 (12.59) | Clavien Grade II, n/N (%) | Non-obstructive Pyelonephritis | 4 (3.00) | Subcupsular Hematoma | 1 (0.74) | Clavien IIIb, n/N (%) | Steinstrasse | 1 (0.74) |
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Perioperative outcomes.
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Variables | SFR (%) | Complications (N) | Stone size, n | ≤10 mm | 100 | 01 | >10-20 mm | 92.1 | 10 | >20-30 mm | 83.33 | 07 | ≥ 30 mm | 77.77 | 05 | p-Value | 0.0005 | 0.0208 | Mean operation time, min | <30 min (13-29) | 95.12 | 4 | ≥30 min (30-60) | 88.29 | 19 | p-Value | 0.0001 | 0.001 | Lasing time, min | <20 min (13-19) | 92.15 | 5 | ≥20 min (20-60) | 89.28 | 18 | p-Value | 0.059 | 0.015 | Stone location | Lower calyx | 86.20 | 20.68 | Pelvis | 93.42 | 21.05 | Upper/middle calyx | 86.66 | 13.33 |
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Univariate logistic regression analysis for SFR and complication.
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Grade | Complication | I | Mucosal Injury | I | Total hematuria, permanent hematuria | I | Fever | I | Urine retention | II | Urinary tract infection | IIIa | Stone migration | IIIb | Perforation | IIIb | Obstruction due to steinstrasser | IIIb | Extravasation and conversion to open | IVa | Myocardial infarction, pulmonary edema | IVb | Urosepsis | V | Death |
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