|
|
Mixed epithelial and stromal tumour with extension to vesicoureteric junction |
Arun Ramdas Menona,*(),T.P. Rajeeva,Suresh Niveditab,Suraj Hegdea
|
aDepartment of Urology, K.S. Hegde Medical Academy, Mangalore, India bDepartment of Pathology, K.S. Hegde Medical Academy, Mangalore, India |
|
|
Abstract Mixed epithelial and stromal tumour (MEST) is an uncommon renal tumour with a tendency to protrude into the collecting system. We present a 50-year-old woman with a renal tumour extending up to the vesicoureteric junction (VUJ) who was suspected to have an upper tract transitional cell carcinoma for which a nephroureterectomy was performed. Histopathologic examination revealed a MEST arising from the kidney and extending up to the VUJ. To the best of our knowledge, this is the first report of a renal MEST with extension to the VUJ.
|
Received: 05 November 2017
Available online: 30 June 2018
|
Corresponding Authors:
Arun Ramdas Menon
E-mail: dr_arunrmenon@yahoo.com
|
|
|
|
Contrast enhanced computed tomography abdomen. (A) Complex cystic mass of left kidney. The mass is seen extending to the upper ureter; (B) Mass seen extending to mid ureter; (C) Mass seen in lower ureter.
|
|
Gross specimen. (A) Left renal mass with bosselated surface and the lower ureter that has been bivalved showing the mass extending up to the vesicoureteric junction; (B) Specimen with the pelvis and ureter bivalved; (C) Bivalved kidney showing the full extent of the mass.
|
|
Photomicrograph. (A) Parts of cyst wall containing spindle cells and numerous congested blood vessels, lined by flattened to cuboidal epithelium; (B) and (C) Sections of tumour showing microcystic spaces lined by cuboidal epithelium.
|
[1] |
Sountoulides P, Koptsis M, Metaxa L, Theodosiou A, Kikidakis D, Filintatzi C , et al. Mixed epithelial and stromal tumor of the kidney (MEST) simulating an upper tract TCC. Can Urol Assoc J 2012; 6:e23-6.
|
[2] |
Michal M, Syrucek M . Benign mixed epithelial and stromal tumor of the kidney. Pathol Res Pract 1998; 194:445-8.
|
[3] |
Wang C, Lin Y, Xiang H, Fang D, Jiang P, Shen B . Mixed epithelial and stromal tumour of the kidney: report of eight cases and literature review. World J Surg Oncol 2013; 11:207.
|
[4] |
Suzuki T, Hiragata S, Hosaka K, Oyama T, Kuroda N, Hes O , et al. Malignant mixed epithelial and stromal tumor of the kidney: report of the first male case. Int J Urol 2013; 20:448-50.
|
[5] |
Calio` A, Eble JN, Grignon DJ, Delahunt B . Mixed epithelial and stromal tumor of the kidney: a clinicopathologic study of 53 cases. Am J Surg Pathol 2016; 40:1538-49.
|
[6] |
Chu LC, Hruban RH, Horton KM, Fishman EK . Mixed epithelial and stromal tumor of the kidney: radiologic-pathologic correlation. Radiographics 2010; 30:1541-51.
|
[7] |
Kum JB, Grignon DJ, Wang M, Zhou M, Montironi R, Shen SS , et al. Mixed epithelial and stromal tumors of the kidney: evidence for a single cell of origin with capacity for epithelial and stromal differentiation. Am J Surg Pathol 2011; 35:1114-22.
|
[8] |
Zhou M, Kort E, Hoekstra P, Westphal M, Magi-Galluzzi C, Sercia L , et al. Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney are the same disease entity: molecular and histologic evidence. Am J Surg Pathol 2009; 33:72-80.
|
[9] |
Zou L, Zhang X, Xiang H . Malignant mixed epithelial and stromal tumor of the kidney: the second male case and review of literature. Int J Clin Exp Pathol 2014; 7:2658-63.
|
[10] |
Farias JA, Laryea J, Gokden N, Kamel MH . Peritoneal seeding following incomplete resection of mixed epithelial stromal tumor of the kidney: first case report. Urol Ann 2016; 8:114-7.
|
[11] |
Moslemi MK . Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update. Urol J 2010; 7:141-7.
|
[1] |
Michael C. Phung,Andrew R. Rouse,Jayce Pangilinan,Robert C. Bell,Erika R. Bracamonte,Sharfuddeen Mashi,Arthur F. Gmitro,Benjamin R. Lee. Investigation of confocal microscopy for differentiation of renal cell carcinoma versus benign tissue. Can an optical biopsy be performed?[J]. Asian Journal of Urology, 2020, 7(4): 363-368. |
[2] |
Dean Laganosky,Christopher P. Filson,Dattatraya Patil,Viraj A. Master. Survival benefit with extended lymphadenectomy for advanced renal malignancy: A population-based analysis[J]. Asian Journal of Urology, 2020, 7(1): 29-36. |
[3] |
Ling Xie,Yifen Zhang,Chin-Lee Wu. Microphthalmia family of transcription factors associated renal cell carcinoma[J]. Asian Journal of Urology, 2019, 6(4): 312-320. |
[4] |
Fangyuan Zhang, Gang Zhao, Pengjie Wu, Qi An, Xin Chen, Jianye Wang, Dong Wei. Asynchronous abdominal wall and sigmoid metastases in clear cell renal cell carcinoma: A case report and literature review[J]. Asian Journal of Urology, 2019, 6(2): 210-214. |
[5] |
R. Sekar Rishi,Patil Dattatraya,Baum Yoram,Pearl Jeffrey,Bausum Anna,A. Bilen Mehmet,Kucuk Omer,B. Harris Wayne,C. Carthon Bradley,Alemozaffar Mehrdad,P. Filson Christopher,G. Pattaras John,T. Nieh Peter,Ogan Kenneth,A. Master Viraj. A novel preoperative inflammatory marker prognostic score in patients with localized[J]. Asian Journal of Urology, 2017, 4(4): 230-238. |
[6] |
Vinay R. Patel, Bradley A. Morganstern, Louis R. Kavoussi. Persistent cough as a paraneoplastic presenting symptom in six patients with renal cell carcinoma[J]. Asian Journal of Urology, 2017, 4(1): 10-13. |
[7] |
Jun Gong, Manuel Caitano Maia, Nazli Dizman, Ameish Govindarajan, Sumanta K. Pal. Metastasis in renal cell carcinoma: Biology and implications for therapy[J]. Asian Journal of Urology, 2016, 3(4): 286-292. |
[8] |
Zhiying Shao, Andrew Z. Wang, Daniel J. George, Tian Zhang. Novel immunotherapy approaches for metastatic urothelial and renal cell carcinoma[J]. Asian Journal of Urology, 2016, 3(4): 268-277. |
[9] |
Rishi R. Sekar, Claire M. De La Calle, Dattatraya Patil, Sarah A. Holzman, Yoram Baum, Umer Sheikh, Jonathan H. Huang, Adeboye O. Osunkoya, Brian P. Pollack, Haydn T. Kissick, Kenneth Ogan, Viraj A. Master. Major histocompatibility complex I upregulation in clear cell renal cell carcinoma is associated with increased survival[J]. Asian Journal of Urology, 2016, 3(2): 75-81. |
[10] |
Rongfu Liu, Xiangcheng Qin, Chengyong Ji, Weixin Zeng, Yufeng Yang, Wei Tan. Pygopus 2 promotes kidney cancer OS-RC-2 cells proliferation and invasion in vitro and in vivo[J]. Asian Journal of Urology, 2015, 2(3): 151-157. |
[11] |
Jiabin An, Yanchuan Guo, Ting Wang, Allan J. Pantuck, Matthew B. Rettig. Pomegranate extract inhibits EMT in clear cell renal cell carcinoma in a NF-κB and JNK dependent manner[J]. Asian Journal of Urology, 2015, 2(1): 38-45. |
[12] |
Sumanta K. Pal, Paulo Bergerot, Robert A. Figlin. Renal cell carcinoma: An update for the practicing urologist[J]. Asian Journal of Urology, 2015, 2(1): 19-25. |
|
|
|
|