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Use of a modified ureteral access sheath in semi-rigid ureteroscopy to treat large upper ureteral stones is associated with high stone free rates |
Jad Khaled AlSmadia, 1, Xiaohang Lia, b, 1, Guohua Zenga, b, *()
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aDepartment of Urology, Minimally Invasive Surgery Center, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China bGuangdong Key Laboratory of Urology, Guangzhou, China |
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Abstract Objective: To examine differences in outcomes of semi-rigid ureteroscopy (URS) with or without a modified-ureteral-access-sheath (mUAS) to treat large upper ureteral stones. Methods: Patients with single, radio-opaque large upper ureteral stone (≥10 mm) treated using semi-rigid URS between August 2013 and October 2016 were retrospectively evaluated. The stone-free status was determined from Kidney-ureter-bladder (KUB) X-ray films taken on postoperative Day 1 and after 1 month. Results: Of 103 patients meeting inclusion criteria, 43 (41.75%) and 60 (58.25%) were treated with semi-rigid URS with and without mUAS, respectively. The immediate stone-free rate (SFR) for the mUAS group was significantly higher than the non-mUAS group (40 [93.0%] vs. 46 [76.7%]; p = 0.033). The SFR at 1 month was also high for patients treated using mUAS, but not statistically different from patients not treated with mUAS (41 [95.3%] mUAS vs. 51 [85.0%] non-mUAS; p = 0.115). Auxiliary procedure rates were significantly lower for mUAS patients compared to non-mUAS patients (2 [4.7%] vs. 14 [23.3%]; p = 0.01). There were no significant differences in surgical duration and hospital stays, and the overall complication rates were statistically similar for mUAS patients compared to non-mUAS patients (1 [2.3%] vs. 3 [5.0%]; p = 0.638). Conclusion: Application of mUAS to treat large upper ureteric stones was associated with higher immediate SFR and final SFR, and lower auxiliary procedure rates relative to patients treated without use of mUAS. Moreover, the use of mUAS did not lengthen operation duration or hospital stays.
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Received: 18 June 2018
Available online: 07 January 2019
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Corresponding Authors:
Guohua Zeng
E-mail: gzgyzgh@vip.sina.com
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Modified ureteral access sheath. (A) The sheath consisting of a straight distal segment and proximal bifurcated segments; (B) Pressure vent.
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Characteristics | mUAS group, n = 43 | Non-mUAS group, n = 60 | p-Value | Age (mean ± SD, year) | 51.91 ± 13.24 | 48.20 ± 11.04 | 0.934 | Sex ratio (male/female) | 18/25 | 24/36 | 0.505 | BMI (mean ± SD, kg/m2) | 22.80 ± 1.45 | 23.95 ± 1.67 | 0.855 | Having diabetes mellitus, n (%) | 1 (2.3) | 8 (13.3) | 0.076 | Having hypertension, n (%) | 9 (20.9) | 12 (20.0) | 0.550 | Laterality (left/right) | 28/15 | 32/28 | 0.311 | Preoperative UTI, n (%) | 5 (11.6) | 3 (5.0) | 0.270 | Hydronephrosis | No or mild, n (%) | 23 (53.5) | 52 (86.7) | <0.001 | Moderate-severe, n (%) | 20 (45.5) | 8 (13.3) | <0.001 | Stone size (mean ± SD, mm) | 12.66 ± 1.16 | 14.94 ± 1.82 | 0.434 | Stone density (Hounsfield units) | 895.57 ± 70.40 | 776.47 ± 120.09 | 0.275 |
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Patient and stone characteristics.
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| mUAS group, n = 43 | Non-mUAS group, n = 60 | p-Value | Stone free cases at 24-48 h, n (%) | 40 (93.0) | 46 (76.7) | 0.033 | Stone free cases at 1 month, n (%) | 41 (95.3) | 51 (85.0) | 0.115 | Surgery mode laser/pneumatic lithotripsy | 23/17 | 29/31 | 0.690 | Hospital stay (mean ± SD, day) | 1.65 ± 0.21 | 1.95 ± 0.29 | 0.105 | Mean duration of operation (mean ± SD, min) | 38.19 ± 9.23 | 41.19 ± 9.27 | 0.507 | Auxiliary procedures, n (%) | 2 (4.7) | 14 (23.3) | 0.010 | Postoperative complications, n (%) | 1 (2.3) | 3 (5.0) | 0.638 | Mean hemoglobin drop (mean ± SD, g/L) | 1.35 ± 0.60 | 0.50 ± 0.27 | 0.236 |
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Operative and postoperative outcomes.
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