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Asynchronous abdominal wall and sigmoid metastases in clear cell renal cell carcinoma: A case report and literature review |
Fangyuan Zhanga,1,Gang Zhaob,1,Pengjie Wua,Qi Anb,Yang Yangb,Xin Chena,Jianye Wanga,Dong Weia,*()
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a. Department of Urology, Beijing Hospital, The Fifth Clinical Medical School of Peking University,National Center of Gerontology, Beijing, China b.Department of General Surgery, Beijing Hospital, The Fifth Clinical Medical School of Peking University, National Center of Gerontology, Beijing, China |
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Abstract Sigmoid metastasis of renal cell carcinoma (RCC) is very rare. Herein we report a case of pathologically proven asynchronous abdominal wall and sigmoid metastases after a right nephrectomy. An 84-year-old man underwent right radical nephrectomy for clear cell renal cell carcinoma (ccRCC) 13 years ago. Solitary contralateral abdominal wall metastasis was found for left abdominal mass 9 years after nephrectomy. The man experienced melena underwent resection of sigmoid colon tumor in February, 2016. The postoperative pathological examinations revealed that the tumors were metastases of ccRCC. Recurrence more than 5 years after nephrectomy has been accepted as late recurrence by the majority of urologists now. Late recurrence is one of the specific biological behaviors of RCC. Asynchronous late recurrence of abdominal wall and sigmoid metastases in ccRCC has not been reported before. When patients have sigmoid mass after nephrectomy for RCC, doctors may consider the possibility of late recurrence.
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Received: 03 January 2017
Available online: 06 January 2018
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Corresponding Authors:
Fangyuan Zhang,Gang Zhao,Dong Wei
E-mail: dongwei63@yeah.net
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Abdominal computed tomography (CT) shows a 2.5 cm × 1.8 cm similar round low density image in the obliquus externus abdominis of left abdominal wall (arrow: The mass of abdominal metastasis).
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Pelvic magnetic resonance imaging (MRI) shows a 4.3 cm × 5.8 cm × 4.3 cm mass of high signal (compared to muscle) on T2WI at sigmoid, the intestinal cavity becomes narrow (arrow: The mass of sigmoid metastasis).
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Microscopic study of sigmoid: Metastasis of clear cell renal cell carcinoma (40×magnification; Haematoxylin and Eosin stain).
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