The association of benign prostatic hyperplasia with lower urinary tract stones in adult men: A retrospective multicenter study

doi:10.1016/j.ajur.2017.06.008

Asian Journal of Urology, 2018, 5 (2): 118-121 doi: 10.1016/j.ajur.2017.06.008

Original Articles

The association of benign prostatic hyperplasia with lower urinary tract stones in adult men: A retrospective multicenter study

Hung Jung Jae^a,Park Jinsung^b,Tae Kim Won^c,WookKim Hong^d,JoonKim Hyung^d,Hong Sungwoo^e,JoYang Hee^f,Chung Hong^g(

)

^a Department of Urology, Yonsei University, Wonju College of Medicine, Wonju, Korea
^b Department of Urology, Eulji University, College of Medicine, Daejeon, Korea
^c Department of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea
^d Department of Urology, Konyang University, College of Medicine, Daejeon, Korea
^e Department of Urology, Dankook University, College of Medicine, Cheonan, Korea
^f Department of Urology, Cheonan Hospital, Soonchunhyang University, College of Medicine, Cheonan, Korea
^g Department of Urology, Konkuk University, School of Medicine, Chungju, Korea

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Abstract Objective

To examine the relationship between benign prostatic hyperplasia (BPH) and the presence of lower urinary tract stones.

Methods

We retrospectively reviewed the records of men with lower urinary tract stones who presented to three clinical centers in Korea over a 4-year period. We divided the patients into two groups based on the location of urinary stones: Group 1 (bladder calculi) and Group 2 (urethral calculi). We compared the characteristics of both groups and performed univariate and multivariate analyses with a logistic regression model to investigate the relationship between BPH and lower urinary tract stones.

Results

Of 221 patients, 194 (87.8%) had bladder calculi and 27 (12.2%) had urethral calculi. The mean age of Group 1 was higher than that of Group 2 (68.96 ± 12.11 years vs.55.74 ± 14.20 years, p < 0.001). The mean prostate volume of Group 1 was higher than that of Group 2 (44.47 ± 27.14 mL vs. 24.70 ± 6.41 mL, respectively, p < 0.001). Multivariate logistic regression showed that age (OR = 1.075, 95%CI: 1.023-1.129) and prostate volume (OR = 1.069, 95%CI: 1.017-1.123) were independently associated with increased risk for bladder calculi. Upper urinary tract stones and/or hydronephrosisconferred a 3-fold risk for urethral calculi (OR = 3.468, 95%CI: 1.093-10.999).

Conclusion

Age and prostate volume are independent risk factors for bladder calculi. In addition, men with upper urinary tract disease are at greater risk for urethral calculi, which may migrate from the upper urinary tract rather than from the bladder.

Key words： Prostatic hyperplasia Urethra Urinary bladder Urolithiasis Lower urinary tract stones

Received: 28 November 2016 Published: 09 June 2018

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	Hung Jung Jae
	Park Jinsung
	Tae Kim Won
	WookKim Hong
	JoonKim Hyung
	Hong Sungwoo
	JoYang Hee
	Chung Hong

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Cite this article:

Hung Jung Jae,Park Jinsung,Tae Kim Won, et al. The association of benign prostatic hyperplasia with lower urinary tract stones in adult men: A retrospective multicenter study[J]. Asian Journal of Urology, 2018, 5(2): 118-121.

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http://www.ajurology.com/EN/10.1016/j.ajur.2017.06.008 OR http://www.ajurology.com/EN/Y2018/V5/I2/118

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