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Percutaneous nephrolithotomy in octogenarians and beyond: How old is too old? |
Bradley Morganstern, Riccardo Galli, Piruz Motamedinia, David Leavitt, Mohamed Keheila, Eric Ghiraldi, David Hoenig, Arthur Smith, Zeph Okeke
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The Smith Institute for Urology, NorthShore-Long Island Jewish Health System, New Hyde Park, NY, USA |
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Abstract Objective: To specifically report perioperative characteristics and outcomes in patients 80 years and older undergoing percutaneous nephrolithotomy (PCNL). PCNL has been established as feasible in the elderly; however, to our knowledge no one has specifically reported feasibility in patients 80 years and older. Methods: We retrospectively reviewed perioperative data of octogenarians who underwent PCNL at a high stone volume single institution, and matched them to patients <65 years of age by stone burden and sex. Patient demographics, perioperative outcomes and postoperative complications were compared. Results: Thirty-three octogenarians (mean age 83.6 years) with 36 renal units were matched to 67 controls (mean age 48.6 years) with 72 renal units. Octogenarians had a higher mean American Society of Anesthesiologists (ASA) score, more comorbidities, and worse renal function. There were no differences in operative characteristics, length of hospital stay or stone free rates. Of the patients with preoperative urinary decompression (ureteral stent or nephrostomy tube) prior to PCNL, the elderly were more likely to have a history of urosepsis. Octogenarians did not experience more minor Clavien (I-II) or major Clavien (IIIa-IVb) complications. Conclusion: Octogenarians who undergo PCNL were more likely to have cardiovascular comorbidities and a prior history of sepsis. Despite these risk factors, in appropriately selected patients PCNL can be safely and successfully performed in octogenarians without increased perioperative complications relative to a younger cohort.
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Received: 24 April 2015
Published: 29 October 2015
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Corresponding Authors:
Bradley Morganstern
E-mail: bam040880@yahoo.com
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[1] |
Smith R, Osterweil D, Ouslander JG. Perioperative care in the elderly urologic patient. Urol Clin North Am 1996;23:27-41.
|
[2] |
Tonner PH, Kampen J, Scholz J. Pathophysiological changes in the elderly. Best Pract Res Clin Anaesthesiol 2003;17:163-77.
|
[3] |
Donat S, Siegrist T, Cronin A, Savage C, Milowsky M, Herr H. Radical cystectomy in octogenariansddoes morbidity outweigh the potential survival benefits? J Urol 2010;183:2171-7.
|
[4] |
Roghmanna F, Sukumarc S, Ravic P, Trinha V, Meskawia M, Ghanic K, et al. Radical cystectomy in the elderly: national trends and disparities in perioperative outcomes and quality of care. Urol Int 2014;92:27-34.
|
[5] |
Curhan GC. Epidemiology of stone disease. Urol Clin North Am 2007;34:287-93.
|
[6] |
Gupta M, Bolton DM, Gupta PN, Stoller ML. Urolithiasis in renal failure. J Urol 1994;152:1086-90.
|
[7] |
Stoller ML, Bolton D, Lezin M, Lawrence M. Percutaneous nephrolithotomy in the elderly. Urology 1994;44:651-4.
|
[8] |
Sahin A, Atsü N, Erdem E, Oner S, Bilen C, Bakkaloğlu M, et al. Percutaneous nephrolithotomy in patients aged 60 years or older. J Endourol 2001;15:489-91.
|
[9] |
Streem SB. Stone extraction. In: Smith AD, Badlani GH, Bagley DH, et al, editors. Smith's textbook of endourology. St. Louis: Quality Medical Publishing; 1996. p. 239-63.
|
[10] |
Okeke Z, Smith AD, Labate G, D'Addessi A, Venkatesh R, Assimos D, et al. CROES PCNL study group. Prospective comparison of outcomes of percutaneous nephrolithotomy in elderly patients versus younger patients. J Endourol 2012;26:996-1001.
|
[11] |
Dindo D, Demartines N, Clavien P. Classification of surgical complications: anewproposal with evaluationin a cohort of 6336 patients and results of a survey. Ann Surg 2004;240:205-13.
|
[12] |
Benson A, Juliano T, Miller N. Infectious outcomes of nephrostomy drainage before percutaneous nephrolithotomy compared to concurrent access. J Urol 2014;192:770-4.
|
[13] |
Moreno M, Lirola M, Tabar G, Baena G, Tenza T, Encinas L. Incidence of infectious complications after extracorporeal shock wave lithotripsy in patients without associated risk factors. J Urol 2014;192:1446-9.
|
[14] |
Polat F, Yes S, Ak E, Farahvash A, Karaog U, Biri H, et al. Safety of ESWL in elderly: evaluation of independent predictors and comorbidity on stone-free rate and complications. Geriatr Gerontol Int 2012;12:413-7.
|
[15] |
Riley JM, Stearman L, Troxel S. Retrograde ureteroscopy for renal stones larger than 2.5 cm. J Endourol 2009;23:1395-8.
|
[16] |
Ricchiuti DJ, Smaldone MC, Jacobs BL, Smaldone AM, Jackman SV, Averch TD. Staged retrograde endoscopic lithotripsy as alternative to PCNL in select patients with large renal calculi. J Endourol 2007;21:1421-4.
|
[17] |
Resorlu B, Diri A, Atmaca A, Tuygun C, Oztuna D, Bozkurt O, et al. Can we avoid percutaneous nephrolithotomy in high-risk elderly patients using the charlson comorbidity index? Urology 2012;79:1042-7.
|
[18] |
Montage S, Rais-Bahrami S, Seideman C, Rastinehad A, Vira M, Kavoussi L, et al. Delayed haemorrhage after laparoscopic partial nephrectomy: frequency and angiographic findings. BJU Int 2011;107:1460-6.
|
[19] |
Shoag J, Halpern J, Goldfard D, Eisner B. Risk of chronic and end stage kidney disease in patients with nephrolithiasis. J Urol 2014;192:1440-5.
|
[20] |
Kurien A, Baishya R, Mishra S, Ganpule A, Muthu V, Sabnis R, et al. The impact of percutaneous nephrolithotomy in patients with chronic kidney disease. J Endourol 2009;23:1403-7.
|
[21] |
Fassett R. Current and emerging treatment options for the elderly patient with chronic kidney disease. Clin Interv Aging 2014;9:191-9.
|
[22] |
Krambeck A, Lieske J, Li X, Bergstralh E, Melton J, Rule A. Effect of age on the clinical presentation of incident symptomatic urolithiasis in the general population. J Urol 2013; 189:158-64.
|
[23] |
Saucier N, Sinha M, Liang K, Krambeck A, Weaver A, Bergstralh E, et al. Risk factors for CKD in persons with kidney stones: a case-control study in Olmsted County, Minnesota. Am J Kidney Dis 2009;55:61-8.
|
[24] |
Yoshimura K, Utsunomiya N, Ichioka K, Ueda N, Matsui Y, Terai A. Emergency drainage for urosepsis associated with upperurinary tract calculi. J Urol 2005;173:458-62.
|
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