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Acute kidney injury in China: A neglected truth and perspective |
Cheng Yang1,2, Bin Yang3,4
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1. Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China; 2. Shanghai Key Laboratory of Organ Transplantation, Shanghai, China; 3. Department of Infection, Immunity and Inflammation, University of Leicester, Leicester General Hospital, University Hospital of Leicester, Leicester LE1 7RH, UK; 4. Department of Nephrology, Affiliated Hospital of Nantong University, Renal Group, Basic Medical Research Centre, Medical College of Nantong University, Nantong, Jiangsu, China |
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Abstract Acute kidney injury (AKI) affects approximately 13.3 million individuals and contributes to about 1.7 million deaths globally per year. As estimated 85% of those affected live in the developing world [1]. Although there are various measures to prevent or treat AKI, including renal protective drugs and continuous renal replacement therapy, most of them have limited success or are still in their infancy [2,3].
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Received: 06 November 2015
Published: 29 January 2016
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Corresponding Authors:
Bin Yang
E-mail: dryangbin@hotmail.com,by5@le.ac.uk
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[1] |
Mehta RL, Cerdá J, Burdmann EA, Tonelli M, García-García G, Jha V, et al. International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology. Lancet 2015;385: 2616-43.
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[2] |
Hu J, Chen R, Liu S, Yu X, Zou J, Ding X. Global incidence and outcomes of adult patients with acute kidney injury after cardiac surgery: a systematic review and meta-analysis. J Cardiothorac Vasc Anesth 2015 Jun 10. http://dx.doi.org/10. 1053/j.jvca.2015.06.017. pii: S1053-0770(15)00567-4. [Epub ahead of print].
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[3] |
Yang C, Zhang C, Zhao Z, Zhu T, Yang B. Fighting against kidney diseases with small interfering RNA: opportunities and challenges. J Transl Med 2015;13:39.
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[4] |
Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet 2015;385:1975-82.
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[5] |
Yang L, Xing G, Wang L, Wu Y, Li S, Xu G, et al. Acute kidney injury in China: a cross-sectional survey. Lancet 2015;386: 1465-71.
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